摘要
目的:考察不同剂量的60Co-γ射线辐照灭菌对西洋参巴布剂黏附性及主要有效成分含量的影响。方法:建立HPLC测定西洋参巴布剂中3种人参皂苷的含量,比较不同剂量辐照前后西洋参巴布剂的黏附性能及有效成分含量的变化。结果:西洋参巴布剂在不同剂量的60Co-γ辐照前后其黏附性无明显变化,辐照前后西洋参巴布剂人参皂苷Rg1,Re,Rb1含量分别约为8,90,90,22,189μg·cm-2。结论:不同剂量60Co-γ辐照前后西洋参巴布剂的黏附性及3种人参皂苷含量无明显变化。
Objective:To investigate the influence on the adhesive activity and effective component content in American ginseng cataplasm with different radiation doses.Method:A HPLC method was established for the determination of 3 kinds of ginsenoside in American ginseng cataplasm;changes of adhesive activity and main constituents were compared in samples irradiated with different radiation doses.Result:60Co-γ radiation with different radiation didn't lead the adhesive activity of American ginseng Cataplasm to change obviously,and the content of ginsenoside Rg1,ginsenoside Re and ginsenoside Rb1 in American ginseng cataplasm was about 8,90,90,22 and 189 μg·cm-2 respectively before and after 60Co-γ radiation.Conclusion:There is no obvious influence on the adhesive activity and the content of main constituents of American ginseng cataplasm before and after sterilization with the method of 60Co-γ radiation.
出处
《中国实验方剂学杂志》
CAS
北大核心
2013年第8期98-102,共5页
Chinese Journal of Experimental Traditional Medical Formulae
基金
广东省东莞市高等院校科研机构科技计划项目(201010810203)
广东省科技计划项目(2010BB091000001)