不同干燥方法对川芎不同部位丁苯酞含量的影响

Effect of Different Drying Methods on Butylphthalide in Different Parts of Ligusticum chuanxiong

目的:研究不同干燥方法对川芎不同部位丁苯酞含量的影响。方法:采用高效液相色谱法测定不同干燥方法的川芎不同部位中丁苯酞的含量。结果:丁苯酞在进样量0.515 2～5.152 0μg与峰面积呈良好的线性关系(r=0.999 9),定量限为5.515 2 mg·L-1,平均回收率为100.1%,RSD 1.10%(n=9);川芎不同部位丁苯酞的含量从高到低为根茎>茎>叶;不同干燥方法对川芎不同部位丁苯酞含量有一定影响。结论:川芎不同部位的丁苯酞含量不同,川芎全株宜选用晒后烘干的干燥方法。

Objective： To study the effect of different drying methods on butylphthalide in different parts of Ligusticum chuanxiong. Method： The content of butylphthalide in L. chuanxiong from different drying methods and different parts was determined by HPLC. Result： There was a good linear relationship between butylphthalide and peak area when the sample injection was from 0. 515 2-5. 152 0μg （r = 0. 999 9） , the quantification limit was 5. 515 2 mg .L-1, the average recovery was 100.1% , and RSD was 1.10% （n =9）. The butylphthalide content in different parts of L. chuanxiong arranged in descending order was rhizome 〉 stem 〉 leaf. Different drying methods had some influence on the butylphthalide content in different parts of L. chuanxiong. Conclusion：Butylphthalide content in different parts of L. chuanxiong is different. Among the three drying methods, oven- drying after sunshine is the optimal one for L. chuanxiong.