脑脉泰胶囊加复方脑蛋白水解物片治疗老年恢复期脑梗死

Clinical Observations of Naomaitai Capsules Plus Compound Cerebroprotein Hydrolysate Tablets on Old Patients with Convalescing Cerebral Infarction

目的:探讨脑脉泰胶囊加复方脑蛋白水解物片治疗老年恢复期脑梗死的临床疗效。方法:72例老年恢复期脑梗死患者随机分为观察组和对照组各36例。两组均口服阿司匹林肠溶片抗血小板聚集,予以控制血糖、血压,调节血脂等基础治疗。对照组加用复方脑蛋白水解物片,口服,4片/次,3次/d;观察组在对照组基础上加服脑脉泰胶囊,口服,2粒/次,3次/d。两组疗程均为8周。采用简易智能状态检查修正表(MMSE)和日常生活能力量表(ADL)分别对两组的智能状态、日常生活能力进行评价。结果:治疗后观察组MMSE评分高于对照组(P<0.01),ADL评分低于对照组(P<0.05);观察组恢复期中风病疗效总有效率为83.33%优于对照组的61.11%(P<0.05);观察组中医证候疗效总有效率为91.67%优于对照组的66.67%(P<0.05)。结论:脑脉泰胶囊能明显改善脑梗死恢复期患者的认知功能和日常生活能力,对脑梗死恢复期患者神经功能有明显改善作用,并改善了临床症状,提高了疾病疗效。

Objective：To investigate the clinical effects of Naomaitai capsules plus compound cerebroprotein hydrolysate tablets on old patients with convalescing cerebral infarction.Method：Seventy two subjects were randomly divided into observation group and control group（n=36 each）.Both groups were given aspirin enteric-coated tablets to antiplatelet aggregation and were adopted the basic treatment for controlling blood glucose and blood pressure and regulating blood fat.The control group were given compound cerebroprotein hydrolysate tablets,4 tablets each time,tid;Naomaitai capsules was added to the observation group,2 capsules each time,tid,all for 8 weeks.Mental state and daily living ability of the two groups were evaluated by mini-mental status examination（MMSE） and activity of daily living scale（ADL）.Result：The observation group was higher than the control group in the scores of MMSE（P0.01） and was lower than the control groups in the scores of ADL（P0.05）;the total effective rate for convalescent stroke in the observation group was superior to the control group（83.33% vs 61.11%）（P0.05）.The total effective rate for treating traditional Chinese medicine symptom in the observation group was superior to the control group（91.67% vs 66.67%）（P0.05）.Conclusion：Naomaitai capsule can significantly improve cognitive function and daily living ability of patients with convalescing cerebral infarction,and has a significant effect on improving the neurologic function of them,thus it can enhance the curative effect for treating disease;it also has obvious improvement on ＇Fengtanyuxue＇ syndrome and can relieve the clinical symptoms so as to improve the curative effect.