补肾温阳化瘀法治疗子宫内膜异位症30例

Tonifying Kidney Warming Yang Removing Blood Stasis Method of Endometriosis 30 Cases of Clinical Curative Effect Observation

目的:通过检测补肾温阳化瘀法对子宫内膜异位症患者血清糖链抗原-125(CA125)的影响,观察补肾温阳化瘀中药对子宫内膜异位症的治疗作用,并通过检测子宫内膜异位症患者治疗前后血清细胞间黏附分子-1(sICAM-1),血管内皮细胞黏附分子-1(sVCAM-1)的变化,观察细胞黏附分子在子宫内膜异位症发病中的作用。方法:采用补肾温阳化瘀法治疗内异症患者30例,分别于治疗前后于卵泡期相同时间分别抽取空腹肘静脉血,测定治疗前后血清中CA125,sICAM-1,sVCAM-1的含量变化。结果:补肾温阳化瘀法治疗本病总有效率73.33%,补肾温阳化瘀法能降低内异症患者血清中CA125的水平(P<0.01),内异症患者血清sICAM-1,sVCAM-1含量明显升高(P<0.05,P<0.01),经过中药治疗后降低(均P<0.01),有统计学意义。结论:ICAM-1,VCAM-1在子宫内膜异位症发病中起着一定的作用,补肾温阳化瘀法通过降低sICAM-1,sVCAM-1含量从而在对子宫内膜异位症起到治疗作用。

Objective：Through the detection method for the kidney and eliminating stasis article endometriosis patients serum carbohydrate antigen（CA125）,the influence of the kidney and eliminating stasis observe article of traditional Chinese medicine on the treatment of endometriosis role,and through the detection endometriosis patients before and after treatment serum intercellular adhesion molecule-1（sICAM-1）,vascular cell adhesion molecule-1（sVCAM-1） changes,observe cell adhesion molecule in the role of endometriosis disease.Method：The cognition to the kidney and eliminating stasis method in the treatment of patients with different disease 30 cases,before and after treatment in follicular phase the same time were selected hollow cubits venous blood,serum CA125 measurement before and after treatment,sICAM-1,sVCAM-1 content changes.Result：Article the kidney and eliminating stasis method the treatment of this disease with the total effective rate 73.33%,Article the kidney and eliminating stasis method can reduce vision in patients with disease of serum CA125 level（P0.01）;Different disease in patients with serum sICAM-1,sVCAM-1 content increased obviously（P0.05,P0.01）,after Chinese medicine therapy reduced（P0.01）,there is statistical significance.Conclusion：ICAM-1,VCAM-1 in endometriosis disease plays a role cognition to the kidney of endometriosis.The recipe could decrease the value of serum sICAM-1,sVCAM-1 of patients with endometriosis,it is an active recipe to cure endometriosis.