血管性痴呆患者的认知功能与事件相关电位的评价

Evaluation of cognitive function in VD patients with MoCA scale and ERP

目的：探讨蒙特利尔认知评估量表（MoCA）及事件相关电位（ERP）P300在血管性痴呆患者临床诊断中的应用。方法：对40例血管性痴呆患者和38例非痴呆老年患者进行MoCA和ERP检测。结果：血管性痴呆组MoCA评分低于对照组（P〈O．05）；血管性痴呆组ERP的P300成分潜伏期明显长于对照组（P〈0．05），但其波幅平均值却低于对照组（P〈0．05）。结论：MoCA和EPRP300对于血管性痴呆患者的诊断具有明显的临床指导意义。

Objective：To explore the application of Montreal cognitive assessment （MoCA） scale and event related potential （ERP） P300 in the diagnostic Of patients with vascular dementia （VD）. Meth- ods：40 VD patients and 38 non-dementia elder were examined with MoCA scale and auditory ERP respec- tively. Results：The VD patients had lower scores of MoCA as compared with the patients in the control group （P〈0.05） ;the P300 latency in the VD group was obviously longer than that in the control group （P〈0.05） ,but the mean amplitude was lower than the control patients（P〈0.05）. Conclusion： MoCA scale and ERP are meaningful for the clinic diagnostic of patients with VD.