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自噬与鼻咽癌治疗研究进展 被引量:5

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摘要 自噬的水平与肿瘤细胞形成、转移及疗效密切相关。在恶性肿瘤治疗中抑制自噬可导致肿瘤细胞无法清除胞内需降解的细胞器,促进细胞死亡,从而强化治疗效果。通过诱导鼻咽癌细胞自噬性死亡可增强鼻咽癌细胞对放疗的敏感性。本文就自噬与鼻咽癌治疗的研究进展作一综述。
作者 李峰 崔德威
出处 《中华实用诊断与治疗杂志》 2013年第4期316-317,共2页 Journal of Chinese Practical Diagnosis and Therapy
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  • 1Blackburn EH. Structure and function of telomeres [J]. Nature, 1991,350 (6319 ) : 569-573.
  • 2Griffith JD, Comeau L, Rosenfield S, et al. Mammalian telomeres end in a large duplex loop [J]. Cell, 1999,97(4): 503-514.
  • 3Zhou JL, Lu YJ, Ou TM, et al. Synthesis and evaluation of quindoline derivatives as G-quadruplex inducing and stabilizing ligands and potential inhibitors of telomerase[J]. J Med Chem, 2005,48(23) :7315-7321.
  • 4Zhou JM, Zhu XF, Lu Y J, et al. Senescence and telomere shortening induced by novel potent G-quadruplex interactive agents, quindoline derivatives, in human cancer cell lines [J]. Oncogene, 2006,25(4):503-511.
  • 5Liu JN, Deng R, Guo JF, et al. Inhibition of myc promoter and telomerase activity and induction of delayed apoptosis by SYUIQ-5, a novel G-quadruplex interactive agent in leukemia cells [J]. Leukemia, 2007,21(6): 1300-1302.
  • 6Klionsky DJ, Emr SD. Autophagy as a regulated pathway of cellular degradation [J]. Science, 2000,290 (5497): 1717- 1721.
  • 7Mammucari C, Milan G, Romanello V, et al. Fox03 controls autophagy in skeletal muscle in vivo [J]. Cell Metab, 2007, 6(6) :458-471.
  • 8Brunet A, Bonni A, Zigmond M J, et al. Akt promotes cell survival by phosphorylating and inhibiting a Forkhcad transcription factor [J]. Cell, 1999,96(6):857-868.
  • 9Liang XH, JacksonS, Seaman M, et al. Induction of autophagy and inhibition of tumorigenesis by beclin 1 [J]. Nature, 1999,402 (6762) : 672-676.
  • 10Vande Velde C, Cizeau J, Dubik D, et al. BNIP3 and genetic control of necrosis-like cell death through the mitochondrial permeability transition pore [J]. Mol Cell Biol, 2000,20( 15 ) : 5454-5468.

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