长沙市男男性接触人群HIV和梅毒感染横断面调查

Prevalence of HIV,syphilis infection among men who have sex with men in Changsha,China

目的了解长沙市男男性接触人群(MSM)人类免疫缺陷病毒(HIV)和梅毒的感染状况,为制定防治策略提供科学依据。方法在长沙市MSM人群经常活动的浴池、KTV娱乐场所、酒吧、会所等场所中,依据知情同意原则,收集目标人群EDTA-K2抗凝全血和非抗凝全血样本各10ml,分别进行HIV抗体、梅毒抗体检测和HIV核酸PCR检测,同时填写完成1份有关人口信息的简单问卷。结果 800名调查对象以学生、青壮年和高学历人群为主。实验室检出64人(8.00%)HIV-1抗体阳性,86人(10.75%)梅毒抗体阳性。5人(0.68%)HIV Pooled RNA PCR试验阳性,处于急性期HIV感染。结论长沙市MSM人群HIV、梅毒较高感染现状应该引起重视,加大对此类人群行为干预和监测检测势在必行。

Objective To investigate the prevalence of HIV, syphilis infection among men who have sex with men （MSM） in Changsha city, Hunan province of China. Methods Two tubes of 10 ml each with or without EDTA-K2-anticoagulated whole blood samples were collected to test HIV antibody, syphilis antibody and HIV RNA. Meanwhile, a questionnaire including questions like age, marriage, education level, sexual be- havior were asked in a MSM individual gathering places like public bath, KTV or bar. Results Most of the 800 MSM entered in this study were students and young people （〉13 years old） with high school or higher education. The positive rates o{ HIV and syphilis antibodies were 8.00% and 10.75%, respectively; 5 acute HIV infections （0.68%） were found. Conclusions The prevalence of HIV and syphilis infection among MSM in Changsha city of China are considerably high; attention and measures should be taken to control the spread of HIV and syphilis in this special population.