2型糖尿病酮症合并严重高甘油三酯血症1例

Severe hypertriglyceridemia in a patient with type 2 diabetic ketosis—A case report

患者男,43岁,主因"反复口干、头晕半月"入院。患者既往无明确糖尿病史,查体无特殊。入院前查TG 52.22mmol/L(4625.12mg/dl)合并血糖明显升高伴尿酮体10mmol/L。入院后予小剂量胰岛素、低分子肝素及非诺贝特降脂等治疗,TG降至3.28mmol/L(290.51mg/dl)。严重高甘油三酯血症(SHTG)有诱发急性胰腺炎和血栓形成的风险,尽早发现和有效治疗极为重要。

A 43 years old male complained of dry mouth and dizziness for half a month before admission. He had no explicit history of diabetes mellitus, and his physical examination showed no abnormalities. Blood test showed extremely high serum triglyceride （52.22 mmol/L）, hyperglycemia, and urine ketone of 10 mmol/L. Low dose insulin infusion, low-molecular-weight heparin calcium and fenofibrate were used for lipid-lowering. His serum triglyceride rapidly reduced to 3. 28 mmol/L after treatment. Severe hypertriglyceridemia （SHTG） could induce acute pancreatitis and thrombosis. Therefore, early detection and effective management of this condition are of great importance.