化脓性中耳炎合并真菌感染聚维酮碘治疗的临床疗效分析

Clinical efficacy of povidone-iodine in treatment of suppurative otitis media combined with fungal infections

目的探讨分析聚维酮碘治疗化脓性中耳炎合并真菌感染的临床疗效,为临床治疗提供指导依据。方法收集60例慢性化脓性中耳炎合并真菌感染患者,随机分为观察组与对照组,观察组患者予以聚维酮碘治疗,对照组予以3%水杨酸乙醇治疗,治疗一周后比较两组患者临床疗效、听力改善幅度及不良反应。结果观察组患者临床有效率86.67%,明显高于对照组63.33%,差异有统计学意义(P<0.05),听力改善幅度高于对照组(P<0.05),而不良反应发生率3.33%,明显低于对照组的13.33%(P<0.05)。结论聚维酮碘治疗化脓性中耳炎合并真菌感染疗效肯定,可明显改善听力,降低不良反应发生率,值得临床推广。

OBJECTIVE To analyze the clinical efficacy of povidone-iodine in the treatment of suppurative otitis media（SOM） combined with fungal infections so as to guide the clinical treatment.METHODS A total of 60 patients with chronic suppurative otitis media（CSOM） combined with fungal infections were randomly divided into the observation group and the control group,the observation group was given the povidone-iodine for treatment,while the control group was given 3% of salicylic acid ethanol for treatment,after a week,the clinical efficacy,hearing improvement of amplitude and incidence of adverse reactions were compared between the two groups.RESULTS The clinical effective rate of the observation group was 86.67%,significantly higher than 63.33% of the control group,the difference was statistically significant（P0.05）,the improvement in hearing magnitude of the observation group was higher than that of the control group（P0.05）;the incidence of the adverse reaction in the observation group was 3.33%,significantly lower than 13.33% of the control group（P0.05）.CONCLUSION Povidone-iodine is effective in treating the SOM combined with fungal infections and it can significantly improve the hearing and reduce the incidence of adverse reactions,and it is worthy to be promoted in the hospital.