新生儿先天性胸腹裂孔疝36例的诊断与治疗

Diagnosis and treatment of congenital diaphragmatic hernia of 36 newborn infants

目的分析新生儿先天性胸腹裂孔疝的临床表现及诊治经验，以提高其手术成功率及生存质量。方法回顾性分析2007年5月至2012年5月新生几外科收治的36例先天性胸腹裂孔疝患儿的临床表现及治疗结果。结果36例先天性膈疝患儿中，34例行手术治疗，术后生存32例，死亡2例，死因与肺发育不良和肺动脉高压有关。另2例未行手术患儿均死亡。结论新生儿先天性膈疝的病死率较高，应加强产前诊断及产科、新生儿外科的合作，以提高先天性胸腹裂孔疝病婴的生存率。

Objective To analyze the clinical experience of diagnosis and treatment of congenital diaphragmatic hernia in newborn infants, and to improve the operative success rate and quality of life. Methods Thirty-six neonates were diagnosed as congenital diaphragmatic hernia in Zhengzhou Children＇s Hospital from May 2007 to May 2012. The clinical data were retrospectively reviewed. Results Thirty-four cases were treated surgically and 32 cases survived, while 2 cases died. The main causes of death was congenital pulmonary dysplasia and pulmonary artery hypertension. Another 2 cases did not accept surgical treatment and they all died. Conclusions The mortality of congenital diaphragmatic hernia in neonates is still high, should strengthen prenatal diagnosis of congenital diaphragmatic hernia and the cooperation between the obstetric and neonatal surgery, to improve the survival rate of congenital diaphragmatic hernia in newborn infants.