生长抑素治疗肠梗阻的疗效观察

Observed efficacy of somatostain on intestinal obstruction

目的探讨生长抑素在肠梗阻非手术治疗中的疗效。方法分析该院2010年1月至2012年3月间收治的50例非手术治疗肠梗阻患者的临床病历资料,对照组25例,采用常规治疗方法;观察组25例,常规治疗方法的基础上加用生长抑素治疗。比较两组患者预后情况。结果研究数据经统计学分析,观察组缓解率明显高于对照组(P<0.05);观察组胃肠减压量、C反应蛋白、肛门排气恢复例数、平均住院时间与对照组相比,均差异有显著性(P<0.05);观察组治疗后KPS评分显著高于对照组治疗后KPS评分(P<0.05)。结论应用生长抑素治疗肠梗阻,能明显改善患者的临床症状,提高保守治疗的成功率。

Objective To investigate efficacy of somatostain on intestinal obstruction non-surgical treatment. Methods Clinical data were analyzed of 50 patients of our hospital with intestinal obstruction non-surgical treatment, from Jan 2010 to Mar 2012. The patients were assigned into control group 25 cases, conventional treatment methods and observation group 25 cases, somatostatin treatment on the basis of conventional treatment. Prognosis was compared between the two groups. Results Response rate in observation group was signif- icantly higher than that in control group （ P 〈 0.05 ） ; The amount of decompression, C-reactive protein, anal exhaust recovery cases, aver- age length of stay in observation group were significantly（ P 〈 0.05 ） ;different from those in control group. KPS score in observation group after treatment was significantly higher than control group （ P 〈 0.05 ）. Conclusion Applying somatostain to intestinal obstruction can significantly improve patients＇symptoms and their quality of life ,which should be widely applied.