罗哌卡因联合亚甲蓝对肛肠疾病术后疼痛的疗效分析

Analgesic efficacy of methylene blue with ropivacaine on anorectai disease postoperation

将2011年1至12月因肛肠疾病而行手术治疗的患者86例，随机双盲分为两组，各43例，分别行罗哌卡因联合亚甲蓝（观察组）和常规止痛措施处理（对照组）。手术后第6～48小时，疼痛视觉模拟评分法（VAS）评分观察组低于对照组（均P〈0．05），术后第72小时评分差异无统计学意义（P〉0．05）；观察组术后并发症总例数8例（19％）、住院（5．3±2．2）d，低于对照组的15例（35％）和（6．4±1．7）d（均P〈0．05）。罗哌卡因联合亚甲蓝术中注射可有效缓解肛肠手术患者术后疼痛，减少住院天数及并发症发生。

Between January 2011 and December 2011, 86 patients undergoing operation for anorectal disease were randomized in a double-blind manner to receive a mixed injection of methylene blue, ropivacaine and sodium chloride （ observation group, n = 43 ） or traditional analgesic methods （ control group, n =43）. Patients in observation group had less visual analog scale （VAS） scores of pain at 6 -48 h postoperation than control group （P 〈 0. 05 ）. The scores had no significant difference at 72 h postoperation between two groups （ P 〉 0.05 ）. The total postoperative complications （ 8, 19% ） and hospitalization duration [ （5.3 ± 2.2）days ] in observation group were significantly less than those [ 15, 35% and （6.4 ± 1.7） days ] in control group （P 〈 0. 05 ）. A mixed injection of methylene blue and ropivacaine intraoperatively can relieve the postoperative pain of patients with anorectal disease and reduce the incidence of postoperative complications and the duration of hospitalization.