中青年冠状动脉狭窄危险因素调查分析(英文)

Survey and analysis of risk factors for coronary artery stenosis in young and middle-aged people

目的:调查分析中青年冠状动脉狭窄危险因素,为动脉粥样硬化防治策略提供思路。方法:回顾性分析2011年3月至2012年8月经冠状动脉造影证实冠状动脉狭窄的167例患者的危险因素。结果:Logistic多元回归分析显示,冠状动脉狭窄危险因素按β值顺序依次为:高血压(1.784),高脂血症(1.708),吸烟(1.095),腰臀比(0.877),有糖尿病家族史(0.781),高同型半胱氨酸(0.608),血清基质金属蛋白酶-9(0.579),肥胖(0.458),缺乏体育锻炼(0.427),P均<0.01。结论:针对相关危险因素进行早期预防,对于中青年冠状动脉狭窄防治会有至关重要的作用。

Objective：To survey and analyze risk factors for coronary provide thinking for prevention and treatment of atherosclerosis artery stenosis in young and middle-aged people to Methods：The risk factors of 167 patients with cor- onary artery stenosis proved by coronary angiography from Mar 2011 to Jun 2012 were retrospectively analyzed. Re- sults..Logistic multiple regression analysis indicated that risk factors of coronary artery stenosis in turn were hyper- tension（1. 784）, hyperlipidemia（ 1. 708）, smoking （ 1. 095 ）, waist-hip ratio （ 0. 877）, family history of diabetes mellitus （0. 781）, high homocysteine （ 0.608 ）, serum matrix metalloproteinase-9 （ 0. 579 ）, obesity （ 0. 458 ）, lack of exercise （0. 427）, P〈0.01 all according to β value. Conelusion：Early prevention focusing on relative risk factors may play a vital role for prevention and treatment of atherosclerosis in young and middle-aged people.