吸烟对冠心病支架植入术患者预后的影响

Influence of smoking on prognosis of patients with coronary heart disease undergoing stent implantation

目的:探讨吸烟对冠心病支架植入术患者预后的影响。方法:入选2006年8月～2010年8月在我院行冠脉支架植入术患者378例,术后随访两年,根据患者术后是否吸烟将其分为戒烟组(237例)和吸烟组(141例),比较吸烟对两组患者预后的影响。结果:随访两年后,与戒烟组比较,吸烟组患者心绞痛(13.1%比22.0%)、非致死性心梗(1.3%比4.9%)发生率明显升高(P<0.05);而两组患者在全因死亡率(2.9%比2.8%)、因心脏病再住院率(11.0%比8.5%)的差异无显著性(P>0.05)。结论:吸烟对冠心病支架植入术后患者有一定的影响,再发心绞痛及非致死性心肌梗死率显著升高。

Objective： To investigate influence of smoking on prognosis of patients with coronary heart disease （CHD） undergoing stent implantation. Methods： A total of 378 CHD patients undergoing coronary stent implanta- tion in our hospital from Aug 2006 to Aug 2008 were enrolled and followed up for two years after implantation. Ac- cording to smoking or not after implantation, patients were divided into non-smoking group （n = 237） and smoking group （n= 141）. Influence of smoking on prognosis was compared between two groups. Results： Compared with non-smoking group after two-year follow up, there were significant increase in incidence rates of angina pectoris （13.1% vs. 22.0%） and nonfatal myocardial infarction （1.3% vs. 4.9%） in smoking group, P〈0. 05; but there were no significant difference in incidence rates of all-cause death （2.9% vs. 2.8%） and rehospitalization rate （11.0% vs. 8. 5%） caused by heart disease between two groups （P〉0. 05）, Conclusion： Smoking has certain influ- ence on prognosis of patients with coronary heart disease after stent implantation, reccurrence rates of angina pecto- ris and nonfatal myocardial infarction significantly increase.