石菖蒲根茎的化学成分研究

Study on chemical constituents from roots and rhizomes of Acorus tatarinowii

目的研究石菖蒲Acorus tatarinowii根茎的化学成分。方法利用不同的色谱分离纯化方法,并通过理化性质和波谱技术鉴定化合物结构。结果从石菖蒲根茎90%乙醇提取液中分离得到13个化合物,分别鉴定为反式丁烯二酸(1)、烟酸(2)、对羟基苯甲酸(3)、尿嘧啶(4)、N-反式-对羟基苯乙基香豆酰胺(5)、胸腺嘧啶(6)、两型曲霉醌A(7)、丁二酸(8)、石菖蒲醇(9)、石菖蒲醇-12-β-D-葡萄糖苷(10)、β-谷甾醇(11)、2,5-二甲氧基对苯醌(12)、5-羟甲基糠醛(13)。结论化合物1～7均为从菖蒲属植物中首次分离得到。

Objective To study the chemical constituents from the roots and rhizomes of Acorus tatarinowii. Methods Using different chromatographic methods to isolate and purify the constituents of A. tatarinowii, and their structures were identified by physicochemical properties and spectroscopic technology. Results Thirteen compounds were isolated and identified as fumaric acid （1）, nicotinic acid （2）, p-hydroxybenzonic acid （3）, uracil （4）, N-trans-feruloyltyramine （5）, thymine （6）, variecolorquinone A （7）, butanedioic acid （8）, tatarol （9）, tataroside-12-13-D-glucoside （10）, 13-sitosterol （11）, 2, 5-dimethoxy- benzoquinone （12）, and 5-hydroxymethyl-2-furaldehyde （13）. Conclusion Compounds 1--7 are isolated from the plants in Acorus L. for the first time.