食管切除术在Barrett食管治疗中的应用进展

Esophagectomy for the Treatment of Barrett’s Esophagus

Barrett食管(Barrett’s esophagus,BE)是发生食管腺癌的重要危险因素。高度不典型增生(high-gradedysplasia,HGD)到腺癌的治疗方法不尽相同,内镜下治疗和抗反流手术存在较高复发率,食管切除术在HGD到腺癌治疗中能够完整切除病变,治疗效果值得肯定,但也要根据不同分期选择不同的手术方式和淋巴结的清扫范围,预后方面淋巴结转移是一个主要的因素。

Barrett＇s esophagus is considered an important risk factor for the pathogenesis of esophageal adenocarci- noma. Treatment strategies for diseases from high-grade dysplasia （HGD）to adenocarcinoma are different. The recurrence rates of endoscopic treatment and anti-reflux surgery are comparatively higher. Abnormal lesions of the esophagus can be completely resected by esophagectomy for the treatment of HGD to adenocarcinoma, and treatment outcomes are confirmed. But appropriate surgical strategies and lymph node dissection scopes should be chosen according to different cancer staging. Lymph node metastasis is a major factor in determining prognosis.