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甘氨酸对大鼠供肝热缺血再灌注损伤的保护作用

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摘要 肝移植早期并发移植肝术后无功能(Primarynonfunction,PNF)的发生率为2%~23%[1],其发生原因与移植肝组织缺血缺氧一再灌注损伤有极为密切的关系[2]。再灌注损伤对移植肝功能的损害,具有现实意义。甘氨酸是人体内的一种非必需氨基酸,它在保护心、肝、肺的缺血再灌注损伤(ischemicalreperfusioninjury,IRI)中起重要作用[3-5]。本研究旨在探讨甘氨酸预处理对大鼠供肝热缺血再灌注损伤的保护作用。
出处 《内蒙古医学院学报》 2012年第S5期787-788,共2页 Acta Academiae Medicinae Neimongol
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