脑海绵状血管瘤3.0T常规MRI与SWI对比分析

Comparative Analysis of Conventional MRI and SWI in Diagnosing Cerebral Cavernous Angioma At 3.0 T MRI Scanner

目的分析脑海绵状血管瘤(CA)常规MRI、磁敏感加权成像(SWI)表现,评价SWI在CA诊断中的价值。方法回顾性分析经临床随访、手术病理证实的53例CA患者的常规MRI(T1WI、T2WI)、SWI资料。53例均行常规MRI、SWI,其中2例行MRI增强扫描。数据采用SPSS 13.0软件进行统计学分析。直径为数值型变量,用均数±标准差(x珋±s)描述并采用单因素方差分析(One-way ANOVA),两两比较采用LSD-t法,P≤0.05为差异有统计学意义。病灶个数在Excel 2003做直方图描述。结果 T1WI检出病灶共55个,T2WI检出60个;15例表现为斑片状长T1、长T2信号,38例在T1WI、T2WI上表现为网状高、低混杂信号,32例T2WI灶周具有典型"黑环征"。SWI检出病灶84个;53例SWI显示为单发或多发斑片状、结节状低信号。7例合并静脉畸形,表现为"水母头"样低信号或强化。SWI显示病变范围比T1WI、T2WI范围更大,微病灶显示更多。CA最大瘤体直径SWI与T1WI、T2WI比较差异均有统计学意义(P<0.05)。结论 SWI较常规MRI能检出更多微小病灶,提高病灶显示率,在脑CA的定性及定量诊断方面具有重要的临床应用价值。

Objective To analyze the manifestations and diagnostic values of conventional MRI and susceptibility weighted imaging （SWI） in cerebral cavernous angioma （CA）. Methods Conventional MRI （T1WI, T2WI） and SWI data of 53 patients with CA proved clinical follow-up and surgical pathology were retrospectively analyzed. All patients underwent conventional MRI and SWI examinations. Among them, 2 cases underwent contrast-enhanced MRI. Results Fifty-five and 60 lesions were detected on TlWI and T2WI retrospectively, the lesions showed hypo-intensity on Tl WI and hyper-intensity on T2WI in 8 cases ,Mixed hyper-and hypointensity in 45 cases, predominantly hemosiderin ring on T2WI in 32 cases. 84 lesions were detected on SWI. Fifty-three cases showed solitary or muhiple patching, nodosity hypointensity on SWI. Seven CA lesions combined with venous malformation showed ＂Jellyfish＂-like low signal intensity or enhancement. The lesions showed bigger on SWI than on TIWI and TEWI, and SWI could show more lesions than TIWI and T2WI. The biggest lesions diameter of CA between SWI and TlWI, T2WI was statistical significance （ P 〈 0.05 ）. Conclusion SWI is more sensitive in showing small CA lesions than conventional MRI. SWI has more important clinical value in the diagnosis of CA.