超声造影对卵巢良恶性肿瘤鉴别诊断的研究进展

Research advancement in contrast-enhanced ultrasonography for the differential diagnosis of benign and malignant ovarian tumors

卵巢肿瘤是女性生殖器常见肿瘤,晚期恶性卵巢肿瘤死亡率较高。目前超声检查已经成为卵巢肿瘤常用的检查方法,但对于部分囊实性及CA125无明显变化的卵巢肿瘤,良恶性病变的鉴别还存在一定的困难。超声造影能清晰的显示组织及肿瘤内的血管及微血管,动态观察正常组织及肿瘤组织血流灌注状态,同时应用时间-强度曲线进行定量分析,在卵巢肿瘤良恶性鉴别诊断方面具有一定价值。本文将卵巢肿瘤超声造影的现状及其对临床应用价值的研究进展进行阐述。

Ovarian tumor is a common form of female genital neoplasms, in which the malignant ovarian tumor results in a very high mortality. Ultrasonography has become a common method for diagnosing ovarian neoplasms. However, this differential diagnosis is difficult to conduct for some cystic-solid ovarian neoplasms or those without marked changes in CA125 cancer antigen. Studies have demonstrated that a contrast-enhanced ultrasonic examination can clearly show the structures of the blood vessels and capillaries in tu-mors. This method can also allow a dynamic observation of the blood perfusion state in normal and tumor tissues. Time-intensity curves are used for quantitative analysis. Thus, this method is important for diagnosing benign and malignant ovarian tumors. Our paper aimed to elucidate further the clinical application of the enhanced ultrasonography for ovarian tumors.