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Hofmeister效应与包含体的变性和复性 被引量:7

Hofmeister Effect and Incluision Body′s Denaturation and Renaturation
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摘要 Hofmeister效应反映了溶质小分子通过与水分子的相互作用 ,对蛋白质等生物大分子造成的结构上的影响。通过对此效应的深入研究 ,可以从理论上解释许多常见的生理生化现象。蛋白质的变性、复性问题是与Hofmeister效应密切相关的生化基础课题。 Hofmeister effects reflect the influences of small solute molecules on macro-biomolecules through solute-water interactions. Theories concerning those effects can be used to interprete many phenomana in life sciences. The denaturation and renaturation of proteins is one of those basic problems. The application of Hofmeister effect in recombinant product inclusion body denaturation and renaturation in biotechnology is discussed in particular.
作者 李伟 欧阳藩
出处 《生物技术通报》 CAS CSCD 2000年第4期37-40,共4页 Biotechnology Bulletin
关键词 Hofmeoster效应 变性 复性 蛋白质 包含体 Hofmeister effect denaturation and renaturation protein inclusion body
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参考文献10

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