摘要
目的 阐明败血症多重耐药菌分布。方法 对我院 1986年 1月至 1998年 12月 13年住院的170 5例经血培养阳性证实的败血症进行致病菌分布与年代比较、耐药性分析。结果 发现以金葡菌为主的G+ 菌占 49.5 5 %、大肠杆菌为主的 G- 菌占 49.0 6 %、L型菌 0 .93%、真菌 0 .44 % ,复数菌 4.5 1%。葡萄球菌72 5 (4 0 .0 0 % )占首位 ,有上升趋势 ;不动杆菌、克雷伯菌、嗜麦芽黄单胞菌等崛起并增多 ;大肠杆菌、铜绿假单胞菌比例下降。耐苯唑西林金葡菌、表葡菌达 75 % ,大肠杆菌等 G- 杆菌 ,(38~ 6 6 ) %对头孢哌酮、头孢曲松、头孢他啶耐药。结论 金葡菌、大肠杆菌、表葡菌、铜绿假单胞菌、不动杆菌、嗜麦芽黄单胞菌、肺炎克雷伯菌、产气肠杆菌、肠球菌是败血症前
Objective:To illuminate distribution of drug- resistance- m ultiple bacteria of septicem ia. Methods:This retrospective study included170 5 inpatients with septicemia proved by blood culture be- tween January1986 and December1998:comparison of distribution of pathogenic bacteria in different ages and analysis of drug- tolerance.Results:Gram- positive bacteria,mainly Staphylococcus aureus,accounted for49.5 5 percent;gram- negative bacteria,mainly Escherichia coli49.0 6 percent;L bacteria,0 .93percent; fugus,0 .44 percent;multiple- bacteria,4.5 1percent.Staphylococcus aureus,72 5 strains(4 0 .0 0 percent) , were m ost and adding up.Acinetobacter,klebsiella and Xanthomonas maltohilia appeared and increased, while Escherichia coli and Pseudom om as aeruginosa decreased,MRSA and MRSE acconnted for75 per- cent.In gram- negative bacteria included Escherichia coli,there were38to6 6 percent strains tolerating cef- operazone,ceftriaxone and cefatazxidime.Conclusion First nine drug- resistance- multiple bacteria of sep- ticem ia are Staphylococcus aureus,Escherichia coli,Staphylococcus epiderm idis,pseudom onas aeruginosa, Acinetobacter,Xanthomonas maltophilia,Klebsiella pneumoniae,Enterobacter aerogenes and Enterococ- cus respectively.
出处
《中国微生态学杂志》
CAS
CSCD
2000年第4期230-232,共3页
Chinese Journal of Microecology
基金
安徽省科委重点科研项目
关键词
败血症
致病菌变迁
耐药性
septicemia
change of pathogenic bacteria
drug- tolerance