阜阳市1061例艾滋病患者抗病毒治疗效果分析

Effectiveness of antiretroviral therapy on 1 061 AIDS patients in Fuyang City

目的分析阜阳市艾滋病抗病毒治疗的效果,为抗病毒治疗方案提供依据。方法应用国家免费提供的抗病毒治疗药物,对符合治疗条件的1 061例艾滋病患者提供规范抗病毒治疗,定期随访病人体重、检测CD4+T淋巴细胞计数。结果 59.51%的病例体重增加;治疗随访12个月,采用不同治疗方案,随治疗时间的延长,不同基线CD4+T淋巴细胞水平的患者CD4+T淋巴细胞平均计数增加均超过136个/μl,随访24个月,平均计数增加均超过150个/μl;治疗满36个月存活率为87.28%。结论高效抗逆转录病毒治疗(highly active antiretroviral therapy,HAART)方案效果肯定,患者的免疫功能得到重建,达到控制死亡率的目标。

Objective To study the effectiveness of antiretroviral therapy in Fuyang so as to provide scientific evi- dence for antiretroviral therapy. Methods 1 061 AIDS patients were given the free standardized antiretroviral treatment. Blood samples were collected periodically for the detection of weight and CD4 T lymphocyte. Results 59. 51% of AIDS patients gained in weight. CD4 T lymphocyte cell count increased dramatically with baseline of over 136/μl during 12 months of treatment in patients for different treatment schemes, while this increasing happened with baseline of over 150/μl with the increase of months of treatment. The survival rate was 87.28% after 36 months of treatment. Conclusions The highly active antiretroviral therapy （ HAART ） scheme has a certain effect on AIDS patients. The immune function of the patients has been rebuilt, and the mortality rate reached the control goal.