虹膜荧光血管造影对新生血管性青光眼早期诊断的临床意义

The Clinical Significance of Iris Fluorescein Angiography in the Early Diagnosis of Neovascular Glaucoma

目的探讨虹膜荧光血管造影(IFA)对新生血管性青光眼早期诊断的临床意义。方法选取新生血管性青光眼患者38例(58只眼)为研究对象,回顾患者的诊断过程,通过比较IFA和眼前节检查的阳性结果检出率,评价IFA对新生血管性青光眼早期诊断的临床意义。结果 IFA阳性检出58只眼,阳性检出率为100.00%;眼前节检查阳性检出46只眼,阳性检出率为79.31%。阳性检出的眼数和阳性检出率,IFA组均明显优于眼前节组,P<0.05。对IFA的检查结果分析发现,糖尿病、外伤以及缺血性CRVO引起的新生血管性青光眼,阳性检出率明显高于非缺血性CRVO。结论 IFA对糖尿病、外伤以及缺血性CRVO引起的新生血管性青光眼,诊断效果明确,具有良好的特异性和敏感性。

Objective To investigate the clinical significance of iris fluorescein angiography （IFA） in the early diagnosis of neovascular glaucoma. Methods 38 patients （58 eyes） with neovascular glaucoma were analyzed retrospectively. The positive rates of IFA and anterior segment examination were compared to evaluate the clinical significance of IFA for early diagnosis of neovascular glaucoma. Results The positive rate of IFA and anterior segment examination was 100.00% （58 eyes） and 79.31% （46 eyes） respectively, the IFA group were significantly superior to the anterior segment group, the difference between two groups was statistically significant （P〈0.05）. The examination results of the IFA＇s analysis found that the positive rate of neovascular glaucoma caused by diabetes, trauma and ischemic CRVO were significantly higher than neovascular glaucoma caused by non-ischemic CRVO. Conclusions The diagnostic effect of IFA for diabetes, trauma, and ischemic CRVO neovascular glaucoma is clear, and it has good specificity and sensitivity.