摘要
目的探讨植入式静脉输液港(IVAP)与经外周静脉置入中心静脉导管(PICC)在视网膜母细胞瘤患儿化疗中的应用,旨在为患儿化疗提供优化静脉通道的科学依据。方法将本科于2010年3月～2011年12月收治的视网膜母细胞瘤患儿采取正规化学治疗者共42例,随机分成PICC组和IVAP组,每组各21例,年龄4个月～5岁。从置管的成功率、导管留置时间、导管相关性并发症方面比较2种置管方法应用效果的差异。结果 IVAP组与PICC组置管成功率比较差异无统计学意义(P>0.05),IVAP组的平均留置时间显著长于PICC组(P<0.05)。2组的导管感染率、导管堵塞率、导管的脱出移位等方面的比较差异均有统计学意义(P<0.05)。结论 IVAP为临床提供了安全、感染率低、维护方便、不影响患儿的生活与运动、留置时间长的治疗通道,可以减少患儿及家长生活质量的降低程度,值得在临床推广与应用。
Objective Through compare effect of implantable venous access port（IVAP）and peripherally inserted central catheter（PICC） in chemotherapy application,to provide optimal chemotherapy for children with venous channel scientific basis.Methods 41 children taked regular chemotherapy for retinoblastoma in ophthalmonogy department in 2010.3 to 2011.12,were randomly divided into PICC group and IVAP group,each group has 21 people.Compare disposable catheterization success rate,catheter indwelling time,catheter-related complications,maintenance of the catheter during non treatment time etc.of two different method.Results The success rate of catheterization of IVAP group and PICC group without statistical significance（P0.05）.The average indwelling time of IVAP group was significantly higher than that of PICC group（P0.05）.There＇re significantly differences in catheter infection,catheter blockage,catheter displacement rate and so on during two groups（P0.05）.Conclusion IVAP has great effect and could improve the quality of life of patients and their parents,is worth to popularize in the clinical application.
