手术辅助化疗与单纯手术切除治疗结直肠癌合并肝转移效果比较

Surgical Resection with or without Adjuvant Chemotherapy for Colorectal Cancer with Liver Metastasis

为比较结直肠癌合并肝转移患者采用单纯手术切除与手术辅助化疗两种治疗方式的临床效果，回顾性分析56例结直肠癌合并肝转移患者的治疗结果，其中采取单纯手术切除治疗19例（对照组），采取手术辅助化疗治疗37例（观察组）。结果显示，通过治疗后1～3年的随访，观察组比对照组患者生存率明显提高，肿瘤复发控制情况更好。结果表明，手术辅助化疗可提高结直肠癌合并肝转移患者的术后生存率，降低复发率，化疗方案安全可靠。

In order to compare the clinical effect of surgical resection with or without adjuvant chemothera-py for colorectal cancer with liver metastasis in patients with colorectal cancer, a retrospective study was conducted among 56 cases of colorectal cancer with liver metastasis,which 19 cases received surgical resec-tion were selected as the controls, 37 cases received additional adjuvant chemotherapy as observation group. The results showed that after a 1-3 year follow-up, the survival rate of patients got improved signif-icantly in observation group than in the controls and tumor recurrence were better controlled. It is conclu-ded that surgical resection with adjuvant chemotherapy can improve the survival rate of patients with color-ectal cancer with liver metastasis, lower the recurrence rate, and chemotherapy regimen is safe and reliable.