1Kanwar YS,Sun L,Xie P,et al.A glimpse of various pathogenetic mecha-nisms of diabetic nephropathy(J).Annu Rev Pathol,2011;6:395-423.
2Lin S,Sahai A,Chugh SS,et al.High glucose stimulates synthesis of fi-bronectin vis a novel protein kinase C,Rap1b,and B-Raf signal pathway(J).J Boil Chem,2002;277(44):41725-35.
3Schulze PC,Yoshioka J,Takahashi T,et al.Hyperglycemia promotes oxi-dative stress through inhibition of thioredoxin function by thioredoxin-in-teracting protein(J).J Biological Chem,2004;279(29):30369-74.
4Brownlee M.The pathobiology of diabetic complications:a unifying mech-anism(J).Diabetes,2005;54(6):1615-25.
6Advani A,Gilbert RE,Thai K.Expression,localization,and function of the thioredoxin system in diabetic nephropathy(J).J Am Soc Nephrol,2009;20(4):730-41.
3Brownlee M.The pathobiology of diabetic complications:a unifying mechanism[J].Diabetes,2005,54(6):1615-1625.
4Forbes JM,Coughlan MT,Cooper ME.Oxidative stress as a major culprit in kidney disease in diabetes[J].Diabetes,2008,57 (6):1446-1454.
5Nishikawa T,Edelstein D,Du XL,et al.Normalizing mitochondrial superoxide production blocks three pathways of hyperglycaemic damage[J].Nature,2000,404(6779):787-790.
6Lee HB,Yu MR,Yang Y,et al.Reactive oxygen species-regulated signaling pathways in diabetic nephropathy[J].J Am Soc Nephrol,2003,14(8 Suppl 3):S241-S245.
7Ha H,Hwang IA,Park JH,et al.Role of reactive oxygen species in the pathogenesis of diabetic nephropathy[J].Diabetes Res Clin Pract,2008,82(Suppl 1):S42-S45.
8Zalba G,San JG,Moreno MU,et al.Oxidative stress in arterial hypertension; role of NAD(P)H oxidase[J].Hypertension,2001,38 (6):1395-1399.
10Rueckschloss U,Galle J,Holtz J,et al.Induction of NAD (P) H oxi-dase by oxidized low-density lipoprotein in human endothelial cells:antioxidative potential of hydroxymethylglutaryl coenzyme A reduc-tase inhibitor therapy[J].Circulation,2001,104(15):1767-1772.