早期介入干预治疗缺血性心肌病58例临床分析

Clinical Analysis of 58 Patients with Ischemic Cardiomyopathy Treated by Early Intervention

目的:探讨经皮冠状动脉介入治疗在缺血性心肌病(ICM)中的临床应用及疗效预后。方法:2007年7月至2011年10月收治缺血性心肌病患者102例,其中58例为治疗组,行冠脉造影并行冠脉介入干预治疗,44例为对照组,虽有介入指征,但由于多种原因未行介入干预,两组患者均获正规药物治疗。结果:治疗组症状改善及LVEF值变化均显著优于对照组(P<0.05);1年内急性左心衰、急性心肌梗死、心源性猝死等心血管事件的发生率显著低于对照组(P<0.05)。结论:早期介入干预对缺血性心肌病能显著改善患者症状及生存率,且时间越早,疗效越显著。

Objective： To explore the clinical application and prognosis of percutaneous coronary interventional therapy in ischemic eardiomyopathy （ICM）. Methods： 102 patients with ICM were diagnosed and treated from Jul 2007 to Oct 2011. 58 cases as treatment group were undergoing pereutaneous coronary intervention, and the other 44 cases as control group had interventional indications, but they had not interventional treatment for some reasons. The two groups had routine drug treatment. Results： The symptoms improved and LVEF value change in the treatment group were significantly better than those in the control group （P 〈 0.05）. The rate of cardiovascular events such as acute left heart failure, acute myocardial infarction and sudden cardiac death in the treatment group were significantly lower than those in the control group（P 〈 0.05）. Conclusions：Early intervention can significantly improve symptoms and survival rate for the patients with ICM, and the earlier the better.