1例产酶大肠埃希杆菌的用药监护

Pharmaceutical care on a patient with Escherichia coli (ESBL+)infection

目的研究产酶大肠埃希杆菌感染的治疗方法和用药监护。方法对1例肺病感染患者进行病例跟踪,分析更换抗生素的原因,总结使用不同抗生素的使用效果。结果长期使用三代头孢,使产酶大肠埃希杆菌的耐药性增加,但对复合三代头孢仍较敏感。结论随着产酶大肠埃希杆菌耐药性的逐年递增,其抗生素的治疗应做药学监护。

Objective The objective of the article is to study the treatment and pharmaceutical care of Escherichia coli （ESBL＋）infection. Methods By tracking a case of a patient with pulmonary infection, it was analysised the replacement of antibiotics, summarized the effect of different antibiotic. Results The long term use of three generation cephalosporins made the drug resistance of Escherichia coli （ESBL＋）increase. However, the three generation cephalosporin/Enzyme inhibitors were still sensitive to Escherichia coli （ESBL＋）. Conclusion Because the drug resistance of Escherichia coli （ESBL＋）increased year by year, the pharmaceutical care should be done in antibiotic treatment.