冠状动脉造影术后造影剂肾病的危险因素分析

Risk factors of contrast-induced nephropathy in patients after coronary angiography

目的探讨冠状动脉造影术后造影剂肾病（CIN）发生的相关危险因素。方法选择200例行冠状动脉造影患者为研究对象，根据患者术后48～72h是否发生CIN分为CIN组和非CIN组，对其CIN发生的相关危险因素进行分析。结果200例行冠状动脉造影患者中有13例发生CIN，CIN发生率为6．5％（13／200）。Logistic回归分析显示原有肾功能不全、糖尿病、造影剂剂量及高龄与CIN的发生有关（P〈0．05）。结论原有肾功能不全、糖尿病、造影剂剂量及高龄是冠状动脉造影术后CIN发生的危险因素。

Objective To investigate the risk factors of contrast-induced nephropathy （CIN） in patients after coronary angiography. Methods Two hundred patients underwent coronary angiography were enrolled in this study. The patients were divided into CIN group and non-CIN group according to the occurrence of CIN after coronary angiography of 48 - 72 h,and then the related risk factors of CIN were analyzed. Results Thirteen eases of CIN were found in 200 patients, and the occurrence rate was 6.5% （13/200）. logistic regression analysis showed that risk factors of CIN included primary renal insufficiency, diabetes, contrast agent dose and advanced age （P 〈 0.05）. Conclusion Primary renal insufficiency, diabetes, contrast agent dose and advanced age are risk factors of CIN in patients after coronary angiography.