早发型子痫前期患者血小板参数检测的临床价值

Detection of platelet parameters in patients with early-onset preeclampsia and its clinical value

目的探讨早发型子痫前期患者血小板五项参数检测的临床价值。方法对36例早发型子痫前期患者(观察组)及35例健康孕妇(对照组)采血检测血小板五项参数,包括血小板计数(PLT)、血小板压积(PCT)、血小板平均体积(MPV)、血小板体积分布宽度(PDW)及大血小板比率(P-LCR)。结果观察组的PLT、PCT水平低于对照组,而MPV、PDW及P-LCR水平则高于对照组,差异有统计学意义(P<0.01和P<0.05)。早发型子痫前期重度患者的PLT、PCT水平低于轻度患者,而MPV、PDW及P-LCR水平则高于轻度患者,差异均有统计学意义(P<0.01和P<0.05)。结论血小板五项参数检测对于早发型子痫前期的诊断及病情严重程度的判断有一定的临床价值。

Objective To investigate the clinical significance of detecting platelet parameters in early- onset preeclampsia. Methods The platelet five parameters in 36 patients with early-onset preeclampsia （ obser- vation group） and 35 healthy pregnant women （ control group） were detected, including PLT, PCT, MPV, PDW and P-LCR. Results The levels of PLT, PCT in the observation group were lower than the control group, while the levels of MPV, PDW and P-LCR in the observation group were higher than the control group（ P 〈 0.01 or P 〈 0. 05）. The levels of PLT, PCT in severe patients were lower than mild patients, while the levels of MPV, PDW and P-LCR in severe patients were higher than mild patients （P 〈 0. 01 or P 〈 0. 05 ）. Conclusion The detection of platelet five parameters in early-onset preeclampsia have important clinical value for the diagnosis and evaluation of the severity of the disease.