320排动态容积CT灌注成像在肝硬化中的临床应用研究

Study on application of liver perfusion imaging in patients with cirrhosis by 320 row dynamic volume CT

目的研究320排动态容积CT在肝硬化患者灌注成像的作用以及临床上应用效果。方法选取50例肝硬化患者及44例肝脏正常者就诊同时行肝脏320排动态容积CT灌注扫描并对结果进行比较分析。结果肝硬化患者的肝脏曲线和正常肝脏的时间-密度曲线基本一致。肝硬化患者经灌注后左右叶参数无显著性差异。肝硬化患者的肝容积变化与HAP、HPP、HBF等肝脏血流灌注参数有关。结论通过对肝脏灌注成像的方法可以对全肝血流灌注参数进行测量。肝硬化的程度可由肝脏血流灌注参数反应。

Objective It is to approach the clinical application effect and function of liver perfusion imaging in patients with cirrhosis by 320 row dynamic volume CT. Methods Fifty patients with liver cirrhosis and 44 normal cases were perfusion scanned by 320 row dynamic volume CT. The result was compared and analyzed. Results The time-density curve of liver cir- rhosis has no significant difference compared with normal cases. There was no significant difference between the right and left lobe with liver perfusion. The changes of liver volume in cirrhotic patients had closed relations with HAP, HPP, HBF and oth- er hepatic perfusion parameters. Conclusion Hepatic perfusion imaging can measure the whole liver perfusion parameters. De- gree of cirrhosis can be classified by liver perfusion parameters.