中枢神经系统感染血清心肌酶及NO变化研究及意义

Change of serum myocardial enzyme and NO in patients with central nervous system infection

目的:探讨分析中枢神经系统感染患者血清心肌酶及NO水平的变化情况。方法:选取74例中枢神经系统感染患者为观察组,同期进行体检的74名健康人员为对照组,后将两组的血清心肌酶及NO水平进行检测及比较,并将观察组中不同分类及严重程度患者的血清心肌酶及NO进行比较。结果:观察组的血清CK、CK-MB、LDH、α-HBDH及NO水平均明显高于对照组,且观察组中重型患者上述指标水平明显高于轻型患者,而化脓性脑膜炎患者明显高于其他分型患者,差异有统计学意义(P<0.05)。结论:中枢神经系统感染患者血清心肌酶及NO水平均明显高于健康人,对疾病严重程度和分型的了解也有一定的价值。

Objective. To study the change of serum myocardial enzyme and NO INpatients with central nervous system infection. Methods;A total of 74 patients with central nervous system infection in our hospital from March2011 to March 2012 were selected as observation group,and 74 healthy persons at the same time were selected as control group. The serum myocardial enzyme and NO of two groups were compared,and those indexes of patients in observation group with different severity and types were also compared. Results：Serum CK,CK-MB, LDH, ^-HBDH and NO of observation group were significantly higher than those of control group, and those indexes of patients with severe disease were significantly higher than those of mild cases,those of patients with purulent meningitis were significantly higher than those of other types （all P〈0.05）. Conclusions：Serum myocardial enzyme and NO of patients with centralnervous system infection are increased,and it is valuable in understanding the severity and types.