感染性休克致急性肾损伤的血流动力学改变及预后相关性研究

Correlation between changes of hemodynamic and prognosis of patients with septic shock induced acute renal injury

目的:分析感染性休克致急性肾损伤的血流动力学改变及预后。方法:对2010年2月～2012年7月本院收治的86例感染性休克合并急性肾损伤患者的临床资料进行回顾性分析,根据患者第28天的生存情况分为生存组(n=44)和死亡组(n=42)。结果:两组患者的一般资料无明显差异,生存组患者的血流动力学改变和肾功能指标明显优于死亡组(P<0.05)。结论:感染性休克致急性肾损伤时血流动力学的改变会影响患者的预后,血流动力学指标可为临床判断患者的预后提供重要的参考信息。

Objective： To analyze the correlation between the changes ot iaemodynamlc ann me prognosis of patients with septic shock induced acute renal injury. Methods. Clinical data of the 86 patients with septic shock induced acute renal injury admitted to our hospital from February 2010 to July 2012 were analyzed retrospectively, and they were divided into survival group （n= 44） and the death group （n= 42） according the prognosis of the patients at the 28th day. Results. There were no significant differences in the general information between the two groups. The index of both the changes of hemodynamic and the renal function in the survival group were significantly better than those in the death group. Conclusions： The changes of hemodynamie can affect prognosis of patients with septic shock induced acute renal injury. The index of the changes of hemodynamic can be used as the observation index to predict the prognosis of patients with septic shock induced acute renal injury.