CT在新生儿缺血缺氧性脑病诊断中的价值

Value of CT in diagnosing neonatal hypoxic-ischemic encephalopathy

目的:探讨CT在新生儿缺血缺氧性脑病中的诊断价值。方法:选取我院出生的足月或早产确诊为新生儿缺氧缺血性脑病(HIE)患儿47例,并设同期分娩无围产期窒息缺氧史患儿26例为对照组,对两组患儿进行CT扫描,取固定点测量相应CT值,进行比较、分析。结果:随着胎龄的增加,脑组织CT值也逐渐增大;足月HIE患儿各部位脑组织CT值较正常新生儿均有降低,且临床分度越重,脑组织CT值越低,组间比较差异显著(P<0.05);早产HIE患儿脑白质、灰质CT值较对照组患儿明显降低(P<0.05)。结论:CT可对HIE患儿作出早期诊断,且能对颅内出血作出定性、定量诊断,对HIE诊断、预后评估有重要价值。

Objective： To discuss the value of CT in diagnosing neonatal hypoxic--ischemic enceph- alopathy （HIE）. our hospital were Methods： A chosen, and total of 47 full-term or premature neonates with confirmed HIE delivered in 26 neonates without perinatal hypoxia or asphyxiation history delivered inthe same period were set as control group. CT scan was performed for all neonates, and CT values of fixed points were collected for comparison and analysis. Results;CT values of brain tissues increased as the ges- rational age grew. CT values of full-term HIE neonates, which decreased with the deepening of clinical grading, were lower than that of normal neonates. Differences between groups were significant （P~ 0.05）. CT values of brain white matter and brain grey matter in HIE neonates were significantly lower than that in control group （P^0.05）. Conclusion.. CT, providing early diagnosis for HIE neonates and qualitative and quantitative diagnosis for intracranial hemorrhage, has great significance for diagnosis and prognosis assessment of HIE.