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鼓室内注射鼠神经生长因子加地塞米松治疗突发性耳聋的临床研究 被引量:5

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摘要 目的:观察鼠神经生长因子+地塞米松鼓室内注射治疗突发性耳聋的疗效。方法:将我科收治的71例突发性耳聋患者,分为鼓室内注射鼠神经生长因子+地塞米松治疗组、鼓室内注射地塞米松组和常规治疗组,鼓室内隔日注射1次。3组在治疗10天后和1月后分别复查纯音听力。结果:鼠神经生长因子加地塞米松组和地塞米松鼓室内注射组经5次注射后,总有效达率96.0%,高于地塞米松组77.8%及常规治疗组62.5%。结论:鼠神经生长因子+地塞米松鼓室内注射治疗突发性耳聋较常规治疗的效果好。
机构地区 临安市人民医院
出处 《中国高等医学教育》 2013年第4期145-146,共2页 China Higher Medical Education
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  • 1马志中,黄厚斌.视神经损伤治疗和不全损伤再生研究的回顾[J].解放军医学杂志,2005,30(9):765-767. 被引量:12
  • 2任基浩,卢永德,殷团芳,刘斌,葛益林.地塞米松鼓室内注射治疗难治性突发性感音神经性聋[J].临床耳鼻咽喉科杂志,2006,20(5):219-221. 被引量:34
  • 3Dai CF, Steyger PS, Wang ZM, et al. Expression of TrkA receptors in the mammalian inner ear[J]. Heating Research,2004, 187: 1.
  • 4Pirvola U, Arumae U, Moshnyakov M, et al. Coordinated expression and function of neurotrophins and their receptors in the rat inner ear during target innervation [ J ]. Hear Res, 1994,75 : 131.
  • 5Hantzopoulos PA, Suri C, Glass D J, et al. The low affinity NGF receptor, p75, can collaborate with each of the Trks to potentiate functional responses to the neurotrophins[ J ]. Neuron, 1994, 13 : 187.
  • 6Rosenthal A, Coeddel DV, Nguyen T, et al. Primary structure and biological activity of novel human neurotrophic factor[J]. Neuron, 1990,4 : 767.
  • 7Shahrooz R, Justin Oh, Zhong LT, et al. Induction of apoptosis by the lowaffinity NGF receptor [ J ]. Science, 1993,261 : 345.
  • 8Amendola T, Aloe L. Developmental expression of nerve growth factor in the eye of rats affected by inherited retinopathy: correlative aspects with retinal structural degeneration [ J ]. Arch Ital Biol, 2002, 140: 81.
  • 9Hu ZQ, Ulfendahl M, Olivius NP. NGF stimulates extensive neurite outgrowth from implanted dorsal root ganglion neurons following transplantation into the adult rat inner ear [ J ], Neurobilogy of Disease,2005,18: 184.
  • 10Bennett MR, Gibson WG, Lemon G. Neuron cell death, nerve growth factor and neurotrophic models : 50 year on [ J ]. Aut Neurosci, 2002,95:1.

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