摘要
目的探讨不同HBV-DNA载量慢性乙肝患者血清巨噬细胞移动抑制因子(MIF)和白细胞介素-17(IL-17)的表达意义。方法 106例慢性乙肝患者根据HBV-DNA载量分为三组,高载量组29例,中载量组46例,低载量组37例,测定患者血清MIF和IL-17。结果高载量组和中载量组患者血清MIF和IL-17明显高于低载量组(P<0.01),高载量组MIF和IL-17均明显高于中载量组(P<0.05,P<0.01)。结论慢性乙肝患者血清MIF、IL-17与病毒载量有密切关系。
Objective To study the value of macrophage migration inhibitory factor （MIF） and interleukin-17 （IL-17） in patients with different HBV-DNA load in chronic hepatitis B. Methods 106 patients with chronic hepatitis B were divided into three groups about different HBV-DNA load, the high HBV-DNA load group（n =29 cases） ,the middle HBV-DNA load group（n =46 cases） and the low HBV-DNA load group（n = 37 cases）. Serum MIF and IL-17 were detected. Results MIF and IL-17 in the high HBV-DNA load group and the middle HBV-DNA load group were higher than these in the low HBV-DNA load group （P 〈 0. 01 ）. MIF and IL-17 in the high HBV-DNA load group were higher these in the low HBV-DNA load group （ P 〈 0. 05, P 〈 0.01 ）. Conclnsion Serum MIF, IL-17 in Chronic hepatitis B patients were closely related to the viral load.
出处
《中国实用医药》
2013年第9期7-8,共2页
China Practical Medicine
