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硫氧还蛋白还原酶与循环系统疾病 被引量：1

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摘要 硫氧还蛋白还原酶（thioredoxin reductase,TrxR）是一种包含黄素腺嘌呤二核苷酸（flavin adeninedinucleotide,FAD）结构域的二聚体硒蛋白,是唯一能够催化形成还原型硫氧还蛋白的硒酶。由于其广泛的底物特异性,能参与到各种氧化还原、炎症、细胞凋亡等生理过程中。由TrxR、硫氧还蛋白（Trx）和还原型辅酶（nicotinamide adenine dinucleotidephosphate,NADPH）组成了硫氧还蛋白系统。硫氧还蛋白系统是细胞内最重要的抗氧化系统之一,
作者 袁媛 谷翔
机构地区 九江学院附属医院心内科
出处 《实用临床医学（江西）》 CAS 2013年第2期130-133,135,共5页 Practical Clinical Medicine
关键词 硫氧还蛋白还原酶 二硫化物氧化还原酶 循环系统疾病 信号通路
分类号 R54 [医药卫生—心血管疾病]
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参考文献29

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二级参考文献22

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实用临床医学（江西）
2013年 第2期

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