血清前白蛋白及总胆汁酸检测在肝硬化患者中的临床应用

Albumin and total bile acid are tested the clinician practice in liver sclerosis patient before the serum

目的探讨血清前白蛋白(PA)及总胆汁酸(TBA)检测在肝硬化患者中的临床应用。方法严格按照Child-pugh评分标准进行评分将80例肝硬化患者分为A、B、C组,20例健康体检者作为对照组,分别检测血清PA、TBA水平,并同时检测肝硬化不同病因的血清PA、TBA水平,比较其差异。结果血清PA和TBA水平在Child-pugh A、B、C级各组之间两两比较差异有显著性;而PA在A级与B、C级之间差异有非常显著性(P<0.01),TBA在C级与A、B级之间差异有非常显著性(P<0.01)。同时也显示肝硬化病因不同血清PA、TBA也有差别。结论血清PA、TBA能敏感地反映肝硬化程度,有助于病情及预后判断。

Objective：Albumin（PA） and total clinician practice in liver sclerosis patient of bile acid（TBA） checkout are inquired into before the serum.Methods：Rigorouslying enforce according to Child-pugh to give a mark standard to give a mark to be divided into 80 example liver sclerosis patients A,B and C team,the healthy physical examination persons of 20 examples as the contrast team,respectively checkout serum PA and TBA＇s standard,and at the same time checkout liver sclerosis different the serum PA of cause of disease and TBA＇s standard,compares his difference.Results：At Child-pugh A,B and C the two two comparison difference has a significance between each group of level to serum PA and TBA＇s standard And the difference of PA between A＇s level and B and C＇s level has very the significance（P0.01）,and the difference of TBA between C＇s level and A and B＇s level has very the significance（P0.01）.Also display liver hardening illness also has the difference because of different serum PA and TBAs at the same time.Conchasion：Serum PA and TBA can reflect the liver sclerosis level sensitivelyly,and contribute to state of an illness and prognosis to judge.