宫内节育器与细菌及其L型相关性的研究

STUDY OF RELATION BETWEEN BACTERIAL INFECTION AND IUD

自 1995年 6月～ 1998年底于山东医科大学第一附属医院计划生育门诊选择 148例患者 ,放置有活性的宫内节育器 ( IU D) 32例 (均为有尾丝者 )为 A组 ,放置惰性 IU D者 5 6例为 B组 ;未放置 IU D的育龄妇女 ,其中无生殖器炎症者 30例为 C组 ,有盆腔炎症者 30例为 D组。各组均采用无菌操作取出宫腔内分泌物 ,同步进行了需氧菌、厌氧菌及其 L 型菌的分离培养 ;A、B两组同时取出 IUD做需氧菌培养 ,其培养阳性结果是 :A、B、C三组间无显著性差异 ( P>0 .0 5 ) ;A、B、C与 D组间均有显著性差异 ( P<0 .0 5 ) ;并用免疫酶染色法检测宫腔分泌物涂片中的金黄色葡萄球菌及该菌的 L 型 ,与培养结果相比无显著性差异。用 PCR法检测了单纯疱疹病毒 型 ( HSV- ) ,淋球菌 ( NG) ,解脲脲原体 ( U U)及生殖道衣原体 ( CT) ,结果是 A、B、C三组与 D组均有显著性差异 ( P<0 .0 5 )

In order to investigate the relation between bacterial infection and IUD,uterine secretions and/ or IU Ds from 32 wom en using IUD with end filament ( group A) ,5 6 women using IUD without end filament ( group B) ,30 wom en not using IUD and having no genital infection ( group C) and 30 wom en not using IU D and having genital infection ( group D) were exam ined by bacteria culture,im munoenzymatic staining and PCR.The results showed:there were no significant difference within group A,B and C( P> 0 .0 5 ) ;while there were significant difference when group A,B,C com pated to group D( P<0 .0 5 ) . These results suggested that bacterial infection was not related to using IUD or not.