临床抑郁青少年行为抑制和行为激活系统的特点

The characters of behavioral inhibition system and behavioral activation system in clinical depressed adolescents

目的探讨临床抑郁青少年行为抑制系统（BIS）和行为激活系统（BAS）的特点。方法根据CCMD-3诊断标准，筛选46名临床抑郁青少年，以35名健康青少年为对照组，采用行为抑制／激活系统问卷、Beck抑郁问卷和医院焦虑抑郁量表进行测评。结果（1）单纯抑郁亚组[（13．70±1．72）分]和对照组[（12．714-2．55）分]行为抑制系统得分均高于焦虑共病抑郁亚组[（15．84±2．36）分，P〈0．01]；单纯抑郁亚组[（34．00±4．94）分]、焦虑共病抑郁亚组[（35．88±6．80）分]行为激活系统得分低于对照组[（39．11±5．06）分，P〈0．05]；（2）首发[（15．284-1．56）分]和复发抑郁组[（14．96±2．63）分]行为抑制系统得分高于对照组[（12．71±2．55）分，P〈0．01]；复发抑郁组[（34．58±6．63）分]行为激活系统得分则较低（P〈0．01）；（3）与对照组相比，服药[（15．30±2．48）分]与未服药抑郁青少年[（14．60±1．82）分]行为抑制系统得分较高（P〈0．01），服药组行为激活系统[（34．52±5．78）分]得分较低（P〈0．01）。结论单纯抑郁与焦虑抑郁共病青少年在行为抑制／激活系统上表现出各自的特点。BIS主要反映抑郁焦虑共病，BAS则反映抑郁症状，BAS可能是反映临床抑郁变化的敏感指标。

Objective To explore the characters of behavioral inhibition/activation systems in clinical depressed adolescents. Methods According to CCMD-3 diagnostic criteria ,46 depressed adolescents and 35 healthy adolescents were selected and assessed by Behavioral Inhibition/Activation System Scale, Beck Depression Inventory and Hospital Anxiety and Depression Scale. Results （ 1 ） Compared with subgroup of mixed depression-anxiety （ 15.84 ± 2.36 ）, depression only subgroup（ 13.70 ± 1.72） and control group（ 12.71 ±2.55） scored higher in B1S （P 〈 0.01 ）. And the two depressed subgroups （34.00 ± 4.94,35.88 ±6.80） scored lower than control group （ 39. 11 ±5.06 ） in BAS （P 〈 0.05 ）. （2） Compared with healthy controls （39.11±5.06 ）, depressed adolescents in first-episode （ 15.28 ＋ 1.56） and recurrent （ 14.96 ±2.63 ） scored higher in BIS （P 〈 0. 01 ）. Adolescents in recurrent （34.58 ±6.63 ） scored lower in BAS（P 〈 0.01 ）. （3） Compared with healthy controls, medication （ 15.30 ＋ 2.48） and unmedicated depressed adolescents （ 14.60 ± 1.82） scored higher in BIS （P 〈 0.01 ）. Medication adolescents （34.52 ± 5.78） scored lower in BAS（P 〈 0.01 ）. Conclusion The BIS/BAS of depressed adolescents have their characters. BIS reflects mixed depression and anxiety. BAS reflects depression and may be a vulnerable index of clinical depression.