双柱串联-超高效液相色谱-质谱法检测水中的4种胺类物质

Simultaneous Determination of Acrylamide,Caprolactam,Benzidine and Aniline by Ultra Performance Liquid Chromatography Tandem Mass Spectrometry with Two Coupled Columns

采用两根液相色谱柱串联的方式,建立了超高效液相色谱串联质谱(UPLC-MS/MS)同时检测丙烯酰胺、己内酰胺、联苯胺和苯胺的方法。地表水样品经过0.2%m滤膜过滤之后即可直接进样,回收率达89.9%～111.5%;废水样品通过固相萃取(SPE)净化,回收率达80.9%～99.8%,本方法对丙烯酰胺、己内酰胺、联苯胺和苯胺的检出限分别0.5,3.0,0.2和0.1%g/L。

An UPLC-MS/MS method with two coupled columns was developed for the simultaneous determination of acrylamide,caprolactam,aniline and benzidine in water samples.The drinking water samples could be injected into the UPLC system just after being filtered through a 0.2 membrane.The recoveries were in the range of 89.9%-111.5%.The waste water samples were purified by solid phase extraction（SPE）,and then were analyzed.The recoveries in waste water were 80.9%-99.8%.The limits of detection（LOD） of acrylamide,caprolactam,benzidine and aniline were 0.5,3.0,0.2 and 0.1 L,respectively.