薄膜包衣提高绿梅止泻颗粒防吸湿性研究

The Thin Film Coating Enhances Green Mei Zhixie the Pellet to Guard Against the Water Absorbant Research

目的研究用薄膜包衣技术提高绿梅止泻颗粒的防吸湿性。方法采用薄膜包衣工艺技术,选取3种包衣液处方,通过对颗粒的溶化时间和防潮性能的综合比较,筛选最佳的包衣材料。结果用高防潮胃溶型薄膜包衣预混剂对本品颗粒包衣后,颗粒溶化时间略有增加,吸湿率比未包衣的颗粒吸湿率低,防潮性好。结论本品可以采用高防潮胃溶型薄膜包衣预混剂进行包衣,对提高其防吸湿性有明显效果。

Objective The research enhances green Mei Zhixie with the thin film coating technology the pellet to guard against the water absorbability. Methods Uses the thin film coating processing technology, selects 3： kind of coating fluid prescription, through to the pellet dissolve time and the moisture- proof performance synthesis comparison, screens the best coating material. Results Dissolves the thin film coating with the high moisture-proof stomach to mix the medicinal preparation in advance after this pellet coating, the pellet dissolve time has the increase slightly, the hygroscopicity has not been lower than the coating pellet hygroscopicity, the moisture-resistance is good. Conclusions This may use the high moisture-proof stomach to dissolve the thin film coating to mix the medicinal preparation to carry on the coating in advance, to enhances it to guard against the water absorbability to have the tangible effect.