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两种三联疗法根除慢性胃炎患者幽门螺杆菌的疗效分析 被引量:2

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摘要 目的观察由奥美拉唑、呋喃唑酮、左氧氟沙星组成的三联疗法与奥美拉唑、阿莫西林、甲硝唑组成的标准三联疗法根除幽门螺杆菌(Hp)的疗效及安全性。方法将108例幽门螺杆菌(Hp)感染的慢性胃炎(非萎缩性胃炎)患者随机分为2组。观察组54例:奥美拉唑20mg每日2次口服、呋喃唑酮100mg每日2次口服、左氧氟沙星200mg每日2次口服。对照组54例:奥美拉唑20mg每日2次口服、阿莫西林1000mg每日2次口服、甲硝唑400mg每日2次口服,停药4周后复查Hp。结果观察组Hp根除率85.18%,对照组根除率46.3%,两组比较有统计学意义(P<0.05)。观察组、对照组不良反应发生率分别为11.1%与14.8%,两组不良反应发生率比较无统计学意义(P>0.05)。结论 "奥美拉唑+呋喃唑酮+左氧氟沙星"三联疗法Hp根除率高,疗效肯定,且药物不良反应低,患者耐受性好,适合临床应用。
出处 《中国医药指南》 2013年第4期522-523,共2页 Guide of China Medicine
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