摘要
目的:观察静脉注射左卡尼汀治疗冠心病心力衰竭的临床疗效。方法:将本院收治的58例冠心病心力衰竭患者随机分为左卡尼汀治疗组30例和对照组28例,左卡尼汀治疗组在常规治疗基础上加用左卡尼汀3.0g1次/d静脉滴注10d,观察用药前后两组临床症状的改善情况以及心率、血压、左室射血分数、6min步行距离的变化,对比观察两组的疗效。结果:左卡尼汀组治疗心力衰竭总有效率(90.0%)明显高于对照组(67.9%)(P<0.05);两组治疗后心功能均有改善,治疗组的心功能改善比对照组更为显著(P<0.05)。结论:常规治疗的基础上应用左卡尼汀可以明显改善冠心病心力衰竭患者的心脏功能,临床治疗效果显著。
Objective： To investigate the efficacy of L-carnitine in patients with heart failure induced by coronary heart disease. Method： Fiftyeight patients with heart failure were randomly divided into L-carnitine group （ 30 cases ） and control group （ 28 cases ） . All the patients received conventional treatment according to guideline for treatment of heart failure. The patients in L-carnitine group received 3.0 g/d L-carnitine intravenously for ten days. Clinical symptoms and heart rate, blood pressure, left ventricular ejection fraction, 6 rain walking distance was analyzed statistically at baseline and ten days after enrollment. Result： The effective rate of the L-camitine group （ 90.0% ） was significantly higher than that of the control group （ 67.9% ） （ P〈0.05 ） . The cardiac function of both groups was improved after treatment, but that of the L-carnitine group was more significant than that of the control group （ P〈0.05 ） . Conclusion： L-camitine can improve the heart function in heart failure patients induced by coronary heart disease.
出处
《中国医学创新》
CAS
2013年第10期24-25,共2页
Medical Innovation of China
关键词
左卡尼汀
冠心病
心力衰竭
L-carnitine
Coronary heart disease
Heart failure
