超声心动图检测妊高征患者孕晚期心功能变化

Evaluation of Cardiac Function in the Last Trimester Pregnancy-induced Hypertension with Echocardiography

目的 利用M型、二维及多普勒超声心动图评估妊高征患者孕晚期心功能变化。方法 临床诊断为妊高征患者 32例 ,正常妊娠组 2 4例 ,常规测量房室腔和大血管内径、室壁厚度、活动幅度 ,计算EF ,FS及室壁增厚率 ;测量二尖瓣E F斜率、二尖瓣及主动脉瓣的血流速度参数等。结果 妊高征组同对照组相比 ,二尖瓣EF下降速率缓慢 (6 38± 2 93cm/svs 9 33± 4 5 3cm/s,P <0 0 5 ) ;E/A明显下降 (1 2± 0 2vs 1 4± 0 2 ,P <0 0 1) ,快速充盈分数减低 (5 7 0 %± 8 5 %vs 6 0 0 %± 7 3% ,P <0 0 5 ) ;左室FS(39 8%± 6 5 %vs 37 1%± 6 9% )、EF(72 2 %±7 1%vs 6 6 4%± 8 2 % )显著增大 (P <0 0 5 ) ,2例患者收缩功能减低。结论 妊高征患者孕晚期可出现心脏舒张功能受损 ,除个别病例外 ,收缩功能无损害。

Purpose The study was to evaluate the changes of cardiac function of the pregnancy-induced hypertension (PIH) patients with echocardiography. Methods The parameters,which were derived from LV diameters,the mitral valve and the aorta pulsed Doppler spectra related to the diastolic and systolic cardiac function were measured in 32 PIH patients and 24 normal pregnants (NP) women. Results The PIH patients had much reduced E-F slope (6 38±2 93cm/s vs 9 33±4 53cm/s, P <0 05),rapid filling fraction (57 0%±8 5% vs 60 0%±7 3%),E/A(1 2±0 2 vs 1 4±0 2, P <0 01) and increased FS(39 8%±6 5% vs 37 1%±6 9%) and EF (72 2%±7 1% vs 66 4%±8 2%).Systolic function was impaired in 2 PIH patients. Conclusion Some PIH patients had diastolic dysfunction and most of patients' systolic function was not impaired in our study except few cases. [