胰腺壶腹周围占位病变术中细针活检的临床价值

Intraoperative fine needle biopsy in pancreatic and periampullary masses

目的 探讨术中细针活检细胞组织学诊断在胰腺壶腹周围占位性病变的诊断价值。方法 对天津肿瘤医院 ,自 1991年 12月至 1996年 12月经手术治疗 87例胰腺壶腹周围占位病变行术中细针活检 ,所有病例均再经手术切除标本 ,或随访结果进一步证实其符合率。结果 87例中细针活检诊断找到恶性肿瘤细胞 49例 ( 5 6% ) ,未找到恶性肿瘤细胞为 3 0例 ( 3 5 % ) ,3例 ( 3 % )为可疑 ,5 ( 6% )例为取材不满意。无假阳性诊断 ,假阴性为 10 %。结论 胰腺壶腹周围占位病变术中细针活检细胞学检查 ,对明确良恶性诊断、指导术式选择是一种较实用 ,有效的方法。

? Objective To evaluate intrapoperative fine needle biopsy (IFNB) in neoplasms of the pancreas and periampulla.Methods 87 cases of IFNB were retrospectively reviewed from Dec.1991 to Dec.1996.All the cases were followed up and compared with cytologic diagnosis.Results Out of 87 cases,for malignant cytologic findings 49 cases were positive,30 cases were negative,3 cases were suspicious,5 cases were undetactable due to unsatisfied sampling.There was no false positive while the overall false negative rate was 10 percent.Conclusions IFNB is a highly accurate cytologic technique of sampling neoplasma of the pancreas and periampullar,which is of great value in differentiating diagnosis and determing the way of operation. 〔