乳腺癌发生发展过程的抑郁障碍特征观察及分析

An Observation and Analysis of the Features of Depressive Disorder in the Incidence and Progression of Breast Cancer

目的探索乳腺癌与抑郁障碍的相关性,及乳腺癌患者患病前后的抑郁障碍特点。方法临床观察经填写汉密尔顿抑郁量表(Hamilton Depression Rating Scale,HAM-D)评估广安门医院肿瘤科门诊40例乳腺癌患者患病前后是否患有抑郁障碍及其程度,以研究抑郁障碍与乳腺癌发生及进展的相关性和特点。结果乳腺癌患者患病前一般抑郁障碍表现的发生率为72.5%(29/40),抑郁症发生率为2.5%(1/40),抑郁障碍总比例为75.0%(30/40);患乳腺癌后患者一般抑郁障碍表现的发生率为60.0%(24/40),抑郁症发生率为7.5%(3/40),抑郁障碍总比例为67.5%(27/40)。结论乳腺癌患者患病前后均可能存在不同程度的抑郁障碍,应引起临床重视并给予相应干预。

Objective To explore the correlation between depressive disorder and breast cancer, and to study the features of depressive disorder in patients before and after suffering breast cancer. Methods Whether 40 breast cancer patients had depressive disorder and their degrees were assessed by filling in Hamilton Depression Rating Scale （HAM-D） at Department of Oncology, Guang′anmen Hospital, China Academy of Chinese Medical Sciences. The correlation between depressive disorder and the occurrence and progression of breast cancer, as well as its features were studied. Results The occurrence of general depressive disorder in breast cancer patients before they suffered from breast cancer was 72.5% （29/ 40 cases）. The occurrence of confirmed depression was 2.5% （1/ 40 cases）. The total depressive disorder rate was 75.0% （30/ 40 cases）. They were 60.0% （24/ 40 cases）, 7.5% （3/ 40 cases）, and 67.5% （27/ 40 cases） in breast cancer patients after they suffered from breast cancer. Conclusion Breast cancer patients have depressive disorder to various levels before and after suffering from breast cancer, which should raise clinical attention and corresponding intervention.