肌腱组织工程生物衍生支架材料

Recent Advance in Tendon Tissue Engineering Using Scaffolding Biomaterials

理想的肌腱组织工程生物衍生材料具有和正常肌腱组织相似的生理活性和功能,植入人体可达到理想的形态修复和功能重建,且具有来源广、不传播疾病、免疫反应弱等优点。生物衍生材料包括天然生物衍生材料和提纯生物衍生材料两大类。本文重点对其性能和作用,以及支架材料制备方法、改良手段和未来发展方向进行讨论。

An ideal biologically derived that tissue engineering material of tendon has biological activities and func- tions, so that it may lead to a perfect effect in histological reparation and reconstruction. In addition, the tissue engi- neering material can avoid disease transmission, be provided from variety of sources and be weak in immune respon- ses. Generally, there are two kinds biologically derived material, i.e. natural biomaterials and purified biomaterials. In this review, researches about the effect, capability and relevant preparation methods, enhancing strategies and the development in the future are discussed.