高血压对冠心病药物洗脱支架择期植入前后中医证型演变规律影响的研究

Study on Changes of Traditional Chinese Medicine Syndrome in Coronary Heart Disease with Hypertension around Intervention Treatment with Drug-eluting Stents in Selected Date

目的:探讨高血压对冠心病药物洗脱支架植入前后中医证型演变规律的影响。方法:对两家三甲医院122例术前诊断为冠心病或疑似冠心病合并高血压且符合其它各项标准的病例,按术前、术后24小时、术后1周、术后1月、术后3月、术后6月完成中医病史的采集及证型的辨别,最后进行整理、统计和分析。结果:合并高血压者的气滞、血瘀、痰浊、气虚、阴虚证分布明显增多(P<0.05或P<0.01)。结论:高血压对CHD药物洗脱支架择期植入前后的证型分布及演变产生了长期的、广泛的影响,导致不同阶段的气滞、血瘀、痰浊、气虚、阴虚等证明显增多。

Objective： To explore Traditional Chinese Medicine（TCM） syndromes in coronary heart disease（CHD） with hypertension distribution and changing rule around intervention treatment with drug-eluting stents（DES） implanted,and influence of syndrome on account of percutaneous coronary intervention（PCI）.Methods： The syndromes of 122 patients of CHD implanted DES with hypertension were analyzed according to six different times around PCI： before,after 24 hours,after 1 week, after 1 month,after 3 months,after 6 months.Results： CHD with hypertension,the counts of Qi stagnation syndrome,blood stasis syndrome,phlegm-turbid syndrome,Qi deficiency syndrome and Yin deficiency syndrome had a significant increase at every times（P〈0.05 or P〈0.01）.Conclusion： It has deeply significant effects to Qi stagnation syndrome,blood stasis syndrome, Phlegm-turbid syndrome,Qi deficiency syndrome and Yin deficiency syndrome in CHD with hypertension by PCI with DES.