苦参苍术口服液的抗炎与止泻作用研究

Study on the Anti-inflammatory and Anti-diarrhea Effects of Kushencangzhu Oral Liquid in Mice

为研究苦参苍术口服液的抗炎、止泻作用,观察了不同剂量苦参苍术口服液对二甲苯致小鼠耳肿胀及蓖麻油致小鼠腹泻的影响。结果显示,苦参苍术口服液能抑制二甲苯导致的小鼠耳肿胀,减轻蓖麻油造成的小鼠腹泻,并呈剂量依赖关系(P<0.05),提示其具有明显的抗炎和止泻作用。该试验可为参苍术口服液的进一步研究与临床应用提供参考。

In order to study the anti -inflammatory and anti -diarrhea effects of Kushencangzhu oral liquid, the experiment was conducted in mice. Xylene -induced ear edema model mice were used to test the anti -inflammatory effect, and castor oil - induced diarrheal model mice were used to evaluate the anti - diarrhea effect. Kushencangzhu oral liquid showed significant inhibition of ear edema formation and anti - diarrhea activity in a dose - related manner compared with the blank control （P 〈 0.05 ）. The results indicate that Kushencangzhu oral liquid has significant anti - inflammatory and anti - diarrhea effects. This study can provide a reference for its further research and clinical uses of Kushencangzhu oral liquid.